Gene Reporter Systems
Promega Intracellular TE Nano-Glo Substrate/Inhibitor, 1,000 assays
The Intracellular TE Nano-Glo Substrate/Inhibitor is a supplement for NanoBRET™ Target Engagement Assays.
Promega Beetle Luciferin, Potassium Salts
Beetle luciferin (also known as D-luciferin) is synthesized as the monopotassium salt and is a substrate for the beetle luciferase reporter systems.
Promega EnduRen™ Live Cell Substrate
An automation-friendly, highly sensitive substrate for Renilla luciferase-based gene reporter and BRET applications.
Promega MTase-Glo Methyltransferase Assay, 400 assays
The MTase-Glo Assay is a bioluminescence-based assay that can be used to monitor the activities of methyltransferases (MTases) and their modulation by small molecules in a wide range of plate formats.
Promega LYN B Kinase Enzyme System
Recombinant full-length human LYN B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. LYN is a 56kDa tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src.
Promega NanoBRET TE HDAC DNA Bundle, 1 each
NanoBRET Target Engagement Assay Components are for use with all NanoBRET Target Engagement Assays.
Invitrogen™ BLOCK-iT™ Inducible Pol II miR RNAi Expression Vector Kit with EmGFP
The BLOCK-iT™ Pol II miR RNAi Expression Vector Kits combine the advantages of traditional RNAi vectors (stable expression and the ability to use viral delivery) with capabilities for tissue-specific expression and multiple target knockdown from the same transcript.
Promega Proteasome-Glo™ Cell-Based Assays
The Proteasome-Glo™ Cell-Based Assays are homogeneous, luminescent assays that measure the chymotrypsin-like, trypsin-like and caspase-like protease activities associated with the proteasome complex in cultured cells.
Promega UDP-Glo Glycosyltransferase Assay + UDP-Glucuronic Acid (UDP-GA), 400 assays
The UDP-Glo Glycosyltransferase Assay is a bioluminescent assay for detecting the activity of glycosyltransferases that use UDP-sugars as donor substrates and release UDP as a product.
Promega ADP-Glo™ Kinase Assay + p70S6K Kinase Enzyme System
Recombinant full-length human p70S6K was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. p70S6K is responsible for the phosphorylation of 40S ribosomal protein S6 and is ubiquitously expressed in human adult tissues.
Promega c-MER Kinase Enzyme System
Recombinant human c-MER (amino acids 578-872) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. c-MER is a tyrosine kinase and a member of the MER/AXL/TYRO3 receptor kinase family.
Promega NanoLuc™ pNL3 Vectors
Configured with NanoLuc Luciferase for use in reporter gene assays of transcriptional control—ideal for cloning of binding site or response element not in need of basic promoters
Promega EGFR Kinase Enzyme System
Recombinant human EGFR (amino acids 695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.
Promega PD-1/PD-L1 Blockade Bioassay, 1 each
The PD-1/PD-L1 Blockade Bioassay is a biologically relevant MOA-based assay that can be used to measure the potency and stability of antibodies and other biologics designed to block the PD-1/PD-L1 interaction.
Promega FcgammaRIIa-H ADCP Reporter Bioassay, Core Kit 5X, 1 each
The FcgammaRIIa-H ADCP Reporter Bioassay is a biologically relevant MOA-based assay that can be used to measure the potency and stability of antibodies and other biologics that specifically bind and activate FcgammaRIIa.